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An acetyl derivative of the amino acid carnitine. A nutrient which occurs naturally in the body. Given orally, acetylcarnitine repletes carnitine in the muscles and other organs. Also crosses the blood-brain barrier more readily than does carnitine, and supports brain energetics and homeostasis. I have personally found this to be most benefical in alterness and stamina.
It is important to note that carnitine supplementation may benefit exercise performance in disease states. Patients with chronic renal failure and peripheral vascular disease have been reported to increase their exercise capacity after treatment with carnitine. In both conditions, muscle carnitine content was shown to be increased with long-term supplementation, although the specific mechanism for any effects of carnitine in these disorders has not been defined. Carnitine supplementation has also been suggested to be beneficial in treating chronic fatigue syndrome .