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The brain is a mass of nerve (neurons) and immune cells (microglia) kept in
balance by hormones to counteract the ongoing and persistent break down called,
"Neurodegeneration". Hormones have very powerful impacts on the brain and are
involved with all steps of keeping the brain in balance.
There is a barrier that keeps the brain clean of anything not wanted called the
Blood-Brain Barrier (BBB). Hormones easily cross the blood-brain barrier, and
there are also enzymes that allow hormones to be made in the brain (not just in
the glands). These hormones are very important and allow the brain to function
at its best.
It is well established that sex hormones have many effects on the brain beyond
their role in reproduction. These hormones also promote the balance of nerve
growth, reduce nerve inflammation, slow down the neurodegeneration, control
nerve repair, assist neurotransmitter assistance, make new nerve pathways and
apparently cause better efficiency known as neuroplasticity. We can age
gracefully and stay in sharp at the same time if we have a plan!
Hormones can help the brains capacity to change connections and behavior in
response to new information, sensory stimulation, development, damage, or
The most recent scientific research on these basic connections shows the
importance of hormones working with brain function. Microglia (the most abundant
cell in the brain) has as one of its many functions hormone production for the
brain. DHEA (A master hormone) and Cholesterol have also been found to produce
hormones in the brain (See Fig 1 at the bottom of this article for full
There are normally enzymes found in the body (that are affected by stress and
blood sugar imbalances) which change hormones and make Estrogen from
Testosterone or make DHEA assist the brain in many ways - from healing to mood,
from cognition to control of non-reproductive behavior.
Note: The research information presented here should not be construed as claims
regarding any product.
Research shows that Estrogen plays a role in brain inflammation, degeneration
and menopausal symptoms. Data suggests that Estrogen replacement therapy may
decrease chances of Alzheimer's and stroke. Evidence shows that a slowdown of
neurodegenerative diseases can occur with Estrogen replacement therapy.
Methods to improve Estrogen balance must be individualized.
Estrovite is a supplement which supports healthy Estrogen receptor site response
and improve Estrogen metabolism. This aids in overall Estrogen balance. Women who suffer symptoms of premenstrual syndrome
and menopause as well as men who convert too much Testosterone into
Many disorders are caused by unbalanced Estrogen levels. These include
Fibrocystic breasts, ovarian cysts, endometriosis, breast cancer, PMS,
Menopause, endometrial cancer, prostate carcinoma and Andropause - to name a
Estrovite also has highly effective compounds for those who are on Estrogen
replacement therapy or Birth Control Pills, both of which increase the level of
Estrogen. As shown in figure 1 below, Estrogen is the last hormone in a long
series of conversions and also needs to be broken down and used.
Many women suffer from poor coordination between their brain and glands as
they age. This can result in symptoms before or during menopause. Lower Estrogen
levels can be due to lowered ability in the brain to effectively use Follicle
Stimulating Hormone (FSH) which triggers release of Estrogen. In these cases,
FSH does not control Estrogen as well as it used to. This function can be
Opticrine. The compounds in
Opticrine have been shown to support
FSH and Estrogen balance in women and LH release in men.
Estrogen can protect the brain during menopause but needs to made, released
and broken down. It may be beneficial to use nutritional support for Estrogen
release, transport, detoxification, and receptor response when taking Estrogen
replacement or birth control pills before Menopause. Nutritional support can
also help in PMS when Estrogen and Progesterone are out of balance.
Men with too much Testosterone converting to Estrogen can be slowed down with
Testanex and broken down with
Summary of the above supplements to support Hormone-Brain Function:
From brain development to adult brain aging and balancing nerve and immune
functions the Thyroid's normal function and hormones are very important. Those
who are born with or develop poor thyroid function may suffer developmental
disorders characterized by reduced mental abilities, lowered sensory perception
and lack of coordination.
suggests that Thyroid hormones may influence the adverse reactions that
accompany brain lesions or neuro-degeneration.
Many traditional approaches to Thyroid balance are no longer safe and
effective. New research developments have brought new understanding in the area
of Thyroid function. For example, supplements containing iodine are considered a
double-edged sword in relation to the Thyroid. It is needed to make a hormone
the Thyroid produces, but can also suppress other Thyroid hormones. This
suppression is due to the alarmingly high intake of salt where iodine has been
added, which covers most of the salt in the United States.
Iodine can increase anti-bodies that attack the Thyroid gland in cases of
under-active Thyroid due to auto-immune causes (which accounts for up to 80% of
hypothyroidism in this country). In these cases, the use of Iodine is harmful,
not beneficial and Oxicell and Ultra D Complex would be of possible benefit.
MyVits carries a multi-vitamin for both men and women called
V. This has been the #1 supplement sold on MyVits for five years running.
Nutrients V contains no Iodine, nor any Iron.
We also carry
Thyroxal, used for Thyroid health. This supplement is Iodine
and Tyrosine free. If a person has too many problems with stress, they should
not use Tyrosine, which is why
Thyroxal is a great option.
Research has shown that there are other causes for Thyroid imbalances than an
excess of Tyrosine and Iodine. Many cases have shown improvement by fixing low
levels of Essential Fatty Acids and improving conversion with
A commonly found cause of Thyroid problems can be found due to Autoimmunity.
This can be supported with
Oxicell and Ultra Vitamin D. The cause could also be
traced to altered Progesterone function, helped by
Summary of Recommended Supplements:
Testosterone has a powerful impact on the Brain. Research shows that the drop in
Testosterone is related to cognitive and brain aging. The Testosterone-Brain
Connection affects basic memory, clear thinking, and Dementia.
Many men must improve their Testosterone levels at some point, but only in
extreme cases should bio-identical Testosterone replacement be encouraged. In
many cases men cannot make enough Testosterone or their bodies over-convert
Testosterone to Estrogen. There are tests in the Expanded Male Hormone panel
from Diagnos-Techs that show where the problem lies. Many men cannot keep the
levels balanced due to an enzyme called Aromatase that converts Testosterone to
Estrogen. This over-conversion can be slowed down with
Testanex, along with
Glysen, which improves insulin function.
The most common reason for low Testosterone in men is stress. The brain
releases LH, which causes Testosterone to be made. When there is too much
stress, suppression of LH occurs. The use of Testosterone therapy in men can
also turn off the release of LH causing a loss of the feedback to the brain. At
the point feedback is lost, the brain stops knowing that it needs to make more
testosterone. Natural botanicals and compounds that nutritionally support LH
pathways in men are found in the product
Low Testosterone in men has been linked to a risk factor for Alzheimer's.
This is caused by a reduction of the secretion of beta-amyloid protein. The
theory is that the increased secretion of this protein with aging tangles up
with the nerve cells, causing poor transmission and leads to nerve cell death
and destruction. Studies are still ongoing but evidence suggests that
improving Testosterone levels can slow down this destructive cycle. Other
studies show that Testosterone can increase the rate of regeneration, increase
nerve growth and protect nerves from cell death due to environmental stress.
Testosterone levels fall as men age. The improvement of Testosterone levels
is a bit tricky. When the brain wants more Testosterone it makes a hormone
called LH to release it. When someone is given Testosterone that does not have
low LH, their own naturally occurring production is stunted. The primary problem
was missed - as it commonly is.
This means no one should be given Testosterone without first checking the LH
level to be sure it is HIGH not LOW and checking for insulin resistance.
Opticrine is our choice when LH is LOW.
Testanex when Estrogens are higher
Progesterone has many effects on healthy brain function including activating
the major cells and nerve signaling. It can also stimulate the growth of nerve
cells which create myelin sheath for brain insulation. Progesterone can activate
the GABA receptors in the brain which creates a calming effect. We have
GABA-Pro as a supplement
which can also improve this.
The Progesterone hormone is important in the regulation of stress, post
partum depression, memory, cognition, PMS, depression and other functions.
Progesterone receptors in the brain are controlled by dopamine.
Studies show that Progesterone is also very powerful in protecting brain
tissue (also called neuro-protective) as well as having an anti-inflammatory
effect. Progesterone has demonstrated speeding the recovery of the brain after
As with any hormone, too much Progesterone or not enough are both problems.
When hormone creams are used they tend to have adverse effects. Hormones can be
stored in the fat and this can cause imbalances.
Progesterone can overload the receptors and the person may develop symptoms of
low Progesterone - even though the opposite is true. The response of hormones is
lost also due the Pituitary gland in the brain not releasing its hormones when
it senses too much present.
If the body is saturated with hormones, eventually the receptor sites develop
resistance, where they are no longer responding to the hormones as well; the
symptoms can be the same as hormone insufficiency. Solving hormone overload may
require stopping all creams for 30-90 days and using
liver support to remove the excess hormones from storage.
Progestaid is designed to support healthy levels of LH (luteinizing hormone),
support a proper Estrogen/Progesterone balance in women, improve fertility, help
manage premenstrual syndrome, and inspire healthy release of LH and
Progesterone. LH imbalances can lead to Progesterone deficiency, Estrogen
dominance, inability to lose weight, infertility, depression, and increased
Opticrine can help restore the Estrogen balance in women whose FSH
hormones from the pituitary gland need to be stimulated to help produce Estrogen
after being placed on Estrogen.
More Information is provided below on how hormones are made and how to balance
their over and under production affecting the brain and body (Fig 1):